Colour Analysis and Normalisation

The HG-MIM Colour Analysis Add-on (supplied free with HG-MIM Pro) facilitates colour based analysis for:

• Automatic tissue annotation (with editable results)
• Area and perimeter based quantification of whole slides or multiple sub-regions (e.g. annotated areas, or automatically generated regular grids)
• Generatng overlay/derrived images based on Colour Normalisation and/or Colour processing methods.

The add on supports a Colour Normalisation plus processing chain that can consist of any of the following elements.

• Colour Normalisation (various methods including Fluorescence microscopy specific methods)
• Colour deconvolution (standard, hand specified, or estimated from annotated or un-annotated images)
• Colour thresholding (hand specified, or estimated from annotated images)
• Probabilistic models (estimated from annotated images)

Applications include:

• IHC analysis
• Collagen quantification
• Special stain analysis